Rituximab in pemphigus foliaceous with autoantibodies against both Desmoglein 1 and Desmoglein 3.

415 5. Varga EA, Kerlin BA, Wurster MW. Social and ethical controversies in thrombophilia testing and update on genetic risk factors for venous thromboembolism. The effect of aspirin on haemostatic activity in the treatment of chronic venous leg ulceration. Pemphigus foliaceous (PF) is generally a benign autoim-mune blistering disease, but in some patients lesions are severe with serious implications in life quality. We report a case of severe PF refractory to standard treatment options successfully treated with rituximab.